Server 2003 "Windows cannot access the specified device, path, or file."

I've been getting this on a lot of my servers lately. I think a recent update to the Internet Explorer Enhanced Security configuration has caused it. Basically, any file that ends up on the server via a network share or through internet explorer cannot be run. It just says: "Windows cannot access the specified device, path, or file.".

I was able to fix it by disabling Internet Explorer Enhanced Security mode. Alternatively, I think adding the local server name to the IE trusted sites should fix it as well.

To disable IE Enhaced Security mode, open Add/Remove Programs, click on Add/Remove Windows Components, uncheck Internet Explorer Enhanced Security and click next.